The utter futility of life without surrender –

“After wandering throughout 8,400,000 species, the soul
eventually takes a human birth. But that human birth is rendered
worthless by those miserable fellows who are so proud of their
bodies that they refuse to take shelter of the lotus feet of Lord
Govinda.”

[from Srila Bhakti Rakshak Sridhar Maharaja’s Sri Prapanna Jivanamritam, 2.8-9]

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